Background. Foramen ovale (FO) flow may be altered in IUGR. This study was designed to test this hypothesis. Methods. Forty pregnant women (24ââ?¬â??38 weeks) were divided into 3 groups: group I (IUGR), group II (adequate growth and maternal hypertension), and group III (normal controls). Impedance across the FO was assessed by the FO pulsatility index (FOPI): (systolic velocityââ?¬â?°Ã¢Ë?â??ââ?¬â?°presystolic velocity)/mean velocity. Statistical analysis utilized ANOVA, Tukey test, and ROC curves. Results. Mean FOPI in IUGR fetuses (nââ?¬â?°=ââ?¬â?°15) was 3.70ââ?¬â?°Ã?±ââ?¬â?°0.99 (3.15ââ?¬â??4.26); in the group II (nââ?¬â?°=ââ?¬â?°12), it was 2.84ââ?¬â?°Ã?±ââ?¬â?°0.69 (2.40ââ?¬â??3.28), and in the group III (nââ?¬â?°=ââ?¬â?°13), it was 2.77ââ?¬â?°Ã?±ââ?¬â?°0.44 (2.50ââ?¬â??3.04) (p = 0.004). FOPI and UtA RI were correlated (rââ?¬â?°=ââ?¬â?°0.375, p = 0.017), as well as FOPI and UA RI (rââ?¬â?°=ââ?¬â?°0.356, p = 0.024) and, inversely, FOPI and MCA RI (rââ?¬â?°=ââ?¬â?°Ã¢Ë?â??0.359, p=.023). Conclusions. The FO flow pulsatility index is increased in fetuses with IUGR, probably as a result of impaired left ventricular diastolic function.
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